Diablo 4 Season 6 introduces a host of formidable endgame bosses that challenge even the most seasoned adventurers. This guide will cover the locations, summoning materials, and loot drops for these fearsome foes.
The endgame Boss is a particular Boss that can be summoned by collecting summoning materials at the end of the game and is an essential part of the gameplay content.
1. Dropped Mythic Unique Items
All endgame bosses can drop the Diablo 4 Mythic Unique items.
Duriel and Andariel are not guaranteed to drop Mythic Unique but are twice as likely to drop Mythic Unique as any other end Boss.
|
Class |
Dropped Mythic Unique |
|
Barbarian |
The Grandfather Shattered Vow Doombringer |
|
Druid |
Ahavarion, Spear of Lycander Shattered Vow Doombringer |
|
Necromancer |
The Grandfather Doombringer |
|
Rogue |
Doombringer |
|
Sorcerer |
Ahavarion, Spear of Lycander Doombringer |
|
Spiritborn |
Nesekem, the Herald Shattered Vow |
|
All Classes |
Melted Heart of Selig Tyrael's Might Andariel's Visage Harlequin Crest Ring of Starless Skies Shroud of False Death Heir of Perdition |
2. The Infernal Hordes
The Infernal Hordes is a new activity introduced in Season 5.
• Summoning Materials: Infernal Compass
• Loot
|
Class |
Dropped Unique Items |
|
Barbarian |
The Third Blade |
|
Druid |
The Basilisk |
|
Necromancer |
The Mortacrux |
|
Rogue |
The Umbracrux |
|
Sorcerer |
Vox Omnium |
|
All Classes |
Locran's Talisman Rakanoth's Wake Endurant Faith Crown of Lucion Shard of Verathiel |
3. Loot from Endgame Bosses
The items listed below have a higher chance of falling from this Boss. Players will still drop unique items that are not on the list and will not always drop unique items each time they kill a Boss.
(1). Andariel
• Location: Hanged Man's Hall.
• Summoning Materials: Pincushioned Doll x 2 Sandscorched Shackles x 2.
• Loot: Drops exclusive cosmetics, specific uniques, and a chance to drop Mythics unique.
(2). Duriel
• Location: Kehjistan level 100 dungeon Gaping Crevasse.
• Summoning Materials: Mucus Slick Eggs x 2 Shards of Agony x 2.
• Loot: Known for dropping high-tier gear and unique items, and a chance to drop Mythics unique.
(3). Loot from Andariel and Duriel
|
Class |
Dropped Unique Items |
|
Barbarian |
Tuskhelm of Joritz the Mighty Azurewrath |
|
Druid |
Dolmen Stone Tempest Roar Azurewrath |
|
Necromancer |
Black River Blood Moon Breeches Azurewrath |
|
Rogue |
Scoundrel's Leathers Cowl of the Nameless Azurewrath |
|
Sorcerer |
Blue Rose Flamescar Azurewrath |
|
Spiritborn |
Sepazontec Rod of Kepeleke |
|
All Classes |
Godslayer Crown Flickerstep Tibault's Will X'Fal's Corroded Signet Soulbrand Banished Lord's Talisman |
(4). Echo of Varshan
• Location: Tree of Whispers - Malignant Burrow dungeon.
• Summoning Materials: Malignant Heart x 4.
• Loot: Offers exclusive cosmetics, unique items, and a chance for Mythic drops.
|
Class |
Dropped Unique Items |
|
Barbarian |
100,000 Steps Gohr's Devastating Grips Ring of Red Furor Fields of Crimson |
|
Druid |
Mad Wolf's Glee Vasily's Prayer Airidah's Inexorable Will Greatstaff of the Crone |
|
Necromancer |
Deathspeaker's Pendant Deathless Visage Ring of the Sacrilegious Soul Bloodless Scream |
|
Rogue |
Skyhunter Condemnation Eyes in the Dark Writhing Band of Trickery |
|
Sorcerer |
Esu's Heirloom Raiment of the Infinite Tal Rasha's Iridescent Loop Staff of Endless Rage |
|
Spiritborn |
Craze of the Dead God Ring of Writhing Moon Ring of the Midday Hunt |
|
All Classes |
Frostburn Mother's Embrace |
(5). Grigoire
• Location: Dry Steppes - the Hall of the Penitent dungeon.
• Summoning Materials: Living Steel x 12.
• Loot: Drops include unique items, Diablo 4 gold, and a chance for Mythic Unique drops.
|
Class |
Dropped Unique Items |
|
Barbarian |
Battle Trance The Butcher's Cleaver Rage of Harrogath Twin Strikes Unbroken Chain |
|
Druid |
Waxing Gibbous The Butcher's Cleaver Insatiable Fury Hunter's Zenith Earthbreaker |
|
Necromancer |
Ebonpiercer Greaves of the Empty Tomb Howl from Below Path of Trag'Oul The Butcher's Cleaver |
|
Rogue |
Word of Hakan Grasp of Shadow Saboteur's Signet Shroud of Khanduras |
|
Sorcerer |
Flameweaver Iceheart Brais Staff of Lam Esen Axial Conduit |
|
Spiritborn |
Peacemonger's Signet Ring of the Midnight Sun |
|
All Classes |
Penitent Greaves |
(5). Lord Zir
• Location: The Darkened Way dungeon in Kehjistan.
• Summoning Materials: Exquisite Blood x 12
• Loot
|
Class |
Dropped Unique Items |
|
Barbarian |
Arreat's Bearing Overkill Ramaladni's Magnum Opus |
|
Druid |
Wildheart Hunger Fleshrender Mjölnic Ryng |
|
Necromancer |
Cruor's Embrace Lidless Wall |
|
Rogue |
Asheara's Khanjar Scoundrel's Kiss |
|
Sorcerer |
Esadora's Overflowing Cameo Fractured Winterglass |
|
Spiritborn |
Jacinth Shell Wushe Nak Pa Band of First Breath |
|
All Classes |
Yen's Blessing Razorplate Temerity |
(6). The Beast in the Ice
• Location: In the Glacial Fissure dungeon
• Summoning Materials: Distilled Fear x 12
• Loot
|
Class |
Dropped Unique Items |
|
Barbarian |
Ancients' Oath Hellhammer Ring of the Ravenous |
|
Druid |
Unsung Ascetic's Wraps Storm's Companion |
|
Necromancer |
Mutilator Plate Ring of Mendeln |
|
Rogue |
Beastfall Boots Windforce Eaglehorn |
|
Sorcerer |
Gloves of the Illuminator Starfall Coronet The Oculus |
|
Spiritborn |
Harmony of Ebewaka Wound Drinker |
|
All Classes |
Fists of Fate Paingorger's Gauntlets Tassets of the Dawning Sky |
Conclusion
Facing these endgame bosses tests your skills and rewards you with some of the best loot in Diablo 4. Prepare well, gather your resources, and dive into the fray to conquer these mighty adversaries.
